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Psychotic reactions are already documented in alcoholic individuals who had been working with oral metronidazole and disulfiram concurrently. Metronidazole vaginal gel should not be administered to patients who may have taken disulfiram inside the previous two months.
There's been no knowledge to this point with the usage of METROGEL-VAGINAL in Expecting individuals. Metronidazole crosses the placental barrier and enters the fetal circulation promptly. No fetotoxicity or teratogenicity was noticed when metronidazole was administered orally to pregnant mice at six occasions the proposed human dose (depending on mg/m²); having said that, in just one small review the place the drug was administered intraperitoneally, some intrauterine deaths were noticed. The relationship of those conclusions on the drug is unknown.
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Keep on to work with this medication until eventually the entire prescribed total is completed, even though indications vanish soon after a couple of days. Halting the medication too early may possibly result in a return on the an infection.
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Metrogel vaginal could communicate with other vaginal creams or douches utilized concurrently, disulfiram cimetidine, lithium, link jnetoto or blood thinners. Inform your health care provider all medicines and dietary supplements you use.
Due to the likely for tumorigenicity revealed for metronidazole in mouse and rat reports, a choice should be created regardless of whether to discontinue nursing or to discontinue the drug, taking into account the significance of the drug to the mother.
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